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Varicella Zoster Immune Globulin

For people exposed to chickenpox but who are not able to receive the chickenpox vaccine, varicella zoster immune globulin (VZIG) can prevent or reduce chickenpox symptoms after exposure. Because it is costly and only provides temporary protection, VZIG is only recommended as treatment for chickenpox in people who are at high risk of developing severe chickenpox symptoms. This includes:
  • Newborns whose mothers have chickenpox 5 days prior to delivery and up to 2 days after delivery
  • Children with leukemia or lymphoma who have not been vaccinated
  • People with cellular immunodeficiencies or other immune problems
  • People receiving drugs, including steroids, that suppress the immune system
  • Pregnant women.
VZIG should be administered as soon as possible, but no later than 96 hours after exposure to chickenpox. If you have had a varicella exposure, and you fit into one of these groups, contact your doctor.
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